Acquisition setting optimization and quantitative imaging for 124I studies with the Inveon microPET-CT system

نویسندگان

  • Nadège Anizan
  • Thomas Carlier
  • Cecilia Hindorf
  • Jacques Barbet
چکیده

Background: Noninvasive multimodality imaging is essential for preclinical evaluation of the biodistribution and pharmacokinetics of radionuclide therapy and for monitoring tumor response. Imaging with nonstandard positronemission tomography [PET] isotopes such as I is promising in that context but requires accurate activity quantification. The decay scheme of I implies an optimization of both acquisition settings and correction processing. The PET scanner investigated in this study was the Inveon PET/CT system dedicated to small animal

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تاریخ انتشار 2017